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色谱耗材
CHC · Laboratory Consumables · 5 models
By Lab Manufacturers China Technical TeamLast reviewed Standards: USP <621> (chromatography), USP <467> (residual solvents), USP <788> (particulate matter in injections)
Chromatography consumables are the inert parts that carry sample and mobile phase through a chromatograph. Liners, septa, frits, PEEK fittings and guard cartridges protect the column, keep background low and keep results reproducible over long sequences.
5 models of Chromatography Consumables
The 5 models below are current configurations; specifications are confirmed on quotation.
气相进样口衬管
A GC inlet liner is a glass tube inside the injection port where the sample vaporises. Its geometry and deactivation affect peak shape and column protection, and correct liner geometry protects the column.
气相进样口隔垫
A GC injection port septum seals the inlet against the needle while resisting temperature and bleed. It must reseal after many injections without adding peaks. Low-bleed material greatly reduces ghost peaks in trace work.
HPLC 色谱柱筛板
An HPLC column frit is a porous disc at the column end that holds the packing in place while allowing mobile phase through. It protects the bed from particles, and its pore size controls pressure.
PEEK 管路和接头
PEEK tubing and fittings form an inert flow path in liquid chromatography, avoiding metal contact and corrosion. They are used for ion analysis and high-salt mobile phases. Narrow tubing reduces peak dispersion.
保护柱芯
A guard column cartridge is a short column of similar packing placed before the analytical column. It retains contaminants so the main column lasts longer. It is replaced frequently and very cheaply.
| Model | Material | Outer diameter | Length | Max temperature | Replacement |
|---|---|---|---|---|---|
| GC Inlet LinerCHC-0001 | Deactivated borosilicate glass | 4 mm | 78.5 mm | Per deactivation, to 350 °C | By injection count |
| GC Injection Port SeptumCHC-0002 | Silicone or PTFE-faced silicone | — | — | Up to 350 °C | Scheduled |
| HPLC Column FritCHC-0003 | Stainless steel, titanium or PEEK | — | — | — | In guard or end fitting |
| PEEK Tubing and FittingsCHC-0004 | PEEK polymer | 1/16 inch | — | — | — |
| Guard Column CartridgeCHC-0005 | — | — | 1–2 cm | — | — |
Indicative values for this product class. Final specifications are confirmed on the quotation and in the calibration documents supplied with the instrument.
Chromatography consumables work by providing a clean, inert flow path and by protecting the analytical column from particulates, involatile residues and reactive analytes. In gas chromatography, the inlet liner holds the injected sample while it vaporises, and its geometry, packing and deactivation affect peak shape and whether involatile material reaches the column; a septum seals the inlet and must reseal after many injections without bleeding siloxanes. In liquid chromatography, frits at the column ends retain the packing while allowing liquid through, and the pore size must be fine enough not to let particles pass but coarse enough to avoid high pressure. PEEK tubing and fittings replace stainless steel where metal interaction or salt corrosion matters. Guard cartridges add a small length of similar packing before the analytical column so contaminants are retained there and the expensive column lasts longer.
Match each consumable to the instrument, the method and the analytes. For GC, choose a liner with a geometry and packing suited to the injection mode, split or splitless, and deactivated for active analytes; choose a septum with the right temperature limit and bleed characteristics for the analyte concentrations and run length. For LC, choose frits of the correct porosity and material, and PEEK or titanium fittings for ion analysis and high-salt mobile phases. Add a guard cartridge that matches the analytical column chemistry, and replace it before contamination reaches the column. Confirm the dimensions, thread types and pressures before ordering, because fittings and frits are not interchangeable between systems. Where trace analysis is done, request lot information and test blanks to confirm low background.
Chromatography Consumables are specified in gas chromatography injection, liquid chromatography and UHPLC, ion chromatography, mass spectrometry interfaces, residual solvent testing and pharmaceutical and food analysis.
Work with Chromatography Consumables is commonly governed by USP <621> (chromatography), USP <467> (residual solvents), USP <788> (particulate matter in injections), ISO/IEC 17025 (testing and calibration laboratories) and USP <1058> (analytical instrument qualification). Instrument certifications such as CE marking are confirmed per configuration and never assumed.
Replace liners, septa and guard cartridges on a schedule based on injection count and sample cleanliness, not only when performance visibly degrades, since contamination develops gradually. Keep a log of replacements and the symptoms that prompted them, such as peak tailing, carry-over or pressure rise. Check the exact part number and dimensions, because a wrong ferrule or liner can leak, leak air into the detector or damage the injection port. Handle frits and liners with clean tools to avoid contamination, and never reuse a liner from one method in another without cleaning and inspection. Confirm that PEEK fittings are used within their pressure and temperature range, and store parts in their packaging. Verify that new lots do not introduce ghost peaks before routine use.
By injection count and sample cleanliness, often every 50–200 injections for dirty samples and less often for clean ones. Symptoms such as peak tailing, carry-over or reduced response indicate it is overdue.
Septum material can bleed siloxanes or other compounds at inlet temperature, and these appear as peaks, especially in trace analysis. Low-bleed septa and a temperature suited to the septum reduce the problem.
Typically 0.2–2 µm, fine enough to retain the packing and block particles but coarse enough to avoid excessive back pressure. The frit material must be compatible with the mobile phase.
For ion chromatography, metal-sensitive analytes, high-salt mobile phases and where corrosion or metal interaction would distort results. PEEK must be used within its pressure and temperature limits.
It retains particulates and strongly retained contaminants before they reach the analytical column, so the main column keeps its performance and lasts longer. The guard should match the analytical column chemistry.
