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样品瓶
VIA · Laboratory Consumables · 5 models
By Lab Manufacturers China Technical TeamLast reviewed Standards: USP <660> (glass containers), EP 3.2.1 (glass containers for pharmaceutical use), ISO 8362 (injection containers and accessories)
Sample vials are small containers with septum closures that hold samples in autosamplers and storage. Autosampler, headspace, crimp, amber and micro-vials are chosen for the instrument, the closure, the mobile phase and the sample volume.
5 models of Vials
The 5 models below are current configurations; specifications are confirmed on quotation.
HPLC 自动进样瓶
An HPLC autosampler vial is a small glass vial with a septa cap sized for the autosampler tray. It holds samples and standards for injection in liquid chromatography with low dead volume options.
顶空瓶
A headspace vial is a sealed glass vial designed to hold a sample and its vapour for gas chromatography. It is crimped or screw capped and rated for the sampler's pressure and temperature.
压盖气相样品瓶
A crimp-top GC vial uses an aluminium crimp seal with a low-bleed septum for gas chromatography. It gives a uniform seal and low background in volatile analysis, with an aluminium crimp seal and low-bleed septum.
棕色样品储存瓶
An amber sample storage vial protects light-sensitive compounds from ultraviolet and short-wavelength light. It is used for standards, drugs and dyes that degrade in clear glass. It blocks ultraviolet and short-wavelength light.
螺口微量样品瓶
A screw-cap micro-vial holds very small sample volumes with a reliable seal for autosamplers. It reduces dead volume when sample is scarce or expensive. It fits standard autosampler trays with 9 mm caps.
| Model | Material | Volume | Closure | Septum | Glass colour |
|---|---|---|---|---|---|
| HPLC Autosampler VialVIA-0001 | Type I borosilicate glass | 1.5–2 mL | Screw or crimp | PTFE-faced silicone | Clear or amber |
| Headspace VialVIA-0002 | Borosilicate glass | 10–22 mL | Crimp or screw | Butyl or PTFE-faced silicone | Clear or amber |
| Crimp-Top GC VialVIA-0003 | Borosilicate glass | 1.5–4 mL | Aluminium crimp | Low-bleed PTFE-faced silicone | — |
| Amber Sample Storage VialVIA-0004 | Amber borosilicate or soda-lime | 1.5–40 mL | Screw cap | — | — |
| Screw-Cap Micro-VialVIA-0005 | Glass or polypropylene | 0.1–1.2 mL | 9 mm screw cap | PTFE-faced silicone | — |
Indicative values for this product class. Final specifications are confirmed on the quotation and in the calibration documents supplied with the instrument.
A sample vial holds a small volume of liquid or headspace gas and is pierced by the autosampler needle through a septum. The vial material must not leach into or adsorb from the sample, so glass, usually borosilicate or Type I, is preferred for organic solvents and trace analysis, and polypropylene is used for aqueous and inorganic samples. The septum is the critical part: silicone, PTFE-faced silicone, butyl or natural rubber are chosen for chemical compatibility, resealing ability and pierce count. The cap and crimp or screw thread must hold the septum flat so no leak or evaporation occurs, because even small losses change concentrations over a long run. Surface treatment and low-adsorption glass help with polar or basic analytes, while amber glass protects light-sensitive compounds. Dimensions follow recognised standards so vials fit autosampler trays and magazines reliably.
Choose the vial to fit the autosampler first, since tray and magazine dimensions are fixed, then choose the closure for the sample and the mobile phase. For reversed-phase HPLC with aqueous and organic mobile phases, a screw-top vial with a PTFE-faced silicone septum is common and convenient. For headspace analysis, use a vial rated for the pressure and temperature of the headspace sampler, with a septum that reseals after each of the several piercings. For GC, crimp-top vials with a low-bleed septum reduce background peaks. Choose amber glass for light-sensitive compounds, and low-adsorption or deactivated glass for basic and polar analytes that bind to active silanol sites. Confirm septum and cap compatibility, volume and any certification for trace metals or leachables, and check that inserts fit the vials and the autosampler needle.
Vials are specified in HPLC and UHPLC autosampling, gas chromatography injection, headspace analysis, standards and sample storage, mass spectrometry sample introduction and trace analysis.
Work with Vials is commonly governed by USP <660> (glass containers), EP 3.2.1 (glass containers for pharmaceutical use), ISO 8362 (injection containers and accessories), USP <661> (plastic components and systems), USP <1664> (assessment of drug product leachables) and GHS labelling requirements. Instrument certifications such as CE marking are confirmed per configuration and never assumed.
Fill vials to the recommended level, usually 50–75 % of the volume, so there is enough headspace for the autosampler and no sample is lost to the septum, and never overfill, because pressure can force liquid out or distort the septum. Use the correct crimp tool and torque, since a loose or over-tightened cap leaks or deforms the septum. Discard vials with damaged septa or distorted caps, and avoid reusing septa, because piercings do not reseal perfectly. Store standards in vials with minimal headspace, seal them well and use amber glass for light-sensitive compounds. Check that vials meet dimensional standards so they do not jam the autosampler, and use only the septa validated for the method, because a different septum can introduce new peaks.
The septum seals the vial and is pierced by the needle. A poor septum leaks, evaporates, sheds particles or introduces new peaks into the chromatogram, so septum choice and cap torque directly affect data quality.
For compounds sensitive to light, such as vitamins, dyes and some drugs, because amber glass filters ultraviolet and short-wavelength visible light that would degrade them during storage or a long run.
Usually 50–75 % of the nominal volume, leaving headspace for the autosampler and reducing contact between liquid and septum. Overfilling risks leakage, while too little liquid can cause the needle to miss the sample.
No. Each piercing leaves a hole that does not reseal perfectly, so reuse allows evaporation, leakage and contamination. Use a new septum and cap for each sample, and discard any with visible damage.
